We read the brain in the light that survives it.

Tacit Neuroscience builds acousto-optic instrumentation for reading population activity in deep tissue — recovering the low-dimensional structure of neural computation from the photons that make it back out.

Three instruments.

1. i

   Acousto-optic tagging

   Ultrasound marks a focal volume; the tagged light carries its address back to the surface.

2. ii

   Wavefront reconstruction

   Scattering is not noise. Given the right prior, a diffuse field is invertible.

3. iii

   Manifold inference

   Population activity is low-dimensional. We estimate the latent geometry directly.

Thought is low-dimensional. Our tools are not.

A hundred thousand neurons move together on a surface a few dozen dimensions wide. Every instrument we have insists on sampling the ambient space instead — one electrode, one cell, one plane at a time. We are building for the manifold, not the ambient space.

Come build the instrument.